What to Take for Tooth Nerve Pain: Is Ibuprofen Best for Your Toothache?

Experiencing Oral Pain? Ibuprofen is Better Than Opioids-Absolute Smile

Publication date: November 11, 2025


A toothache is one of the most painful types of pain, so its onset can cause significant discomfort. In this case, it is necessary to use proven medications. The patient should see a dentist as soon as possible to identify the cause of the pain and begin the appropriate treatment.

Understanding Tooth Nerve Pain

A tooth does not hurt for no reason, so the first step is to determine the cause. Most often, it is related to:

  • Tooth decay. It develops due to the formation of tartar and plaque, which destroy the enamel. The cause is poor oral hygiene. In the early stages, there are no symptoms, however, later on, a particular sensitivity to sweet and cold foods may appear.
  • Inflammation of the tooth nerve (pulpitis). This is a sharp, throbbing pain that occurs when untreated tooth decay causes tissue destruction to reach the nerve. Very often, the pain intensifies at night and can extend to the temples.
  • Gum disease (this can be periodontitis, gingivitis, etc.). Accompanied by bleeding gums and slight aching pain. Caused by dental plaque.

Of course, these are not all types of diseases that exist. Anyway, all pain deserves attention and a responsible approach.

Why is Ibuprofen Commonly Recommended for Toothache

Ibuprofen is one of the most recommended medications for a toothache. It has analgesic and antipyretic effects, thereby relieving pain. In addition, it reduces swelling and is even approved for use in children. It’s all about the composition, which is considered less toxic compared to other drugs.

Other Medicines That Help Toothache

Today, there are many medicines for toothache and other ailments. In addition to ibuprofen, you may consider:

  • Aspirin;
  • Paracetamol;
  • Analgin;
  • Tylenol;
  • Aleve;
  • Acetaminophen, etc.

The main thing is to familiarize yourself with the action of the drug, for whom it is intended, and what contraindications it has. Familiarize yourself with the dosage, as it may vary for each patient. If you have any questions, it is best to consult your doctor.

Comparing Medicines for Tooth Nerve Pain

Anyone who has experienced a toothache knows how it can throw you off balance. At times like these, everyone’s only desire is to get rid of it as quickly as possible and get back to business. Choosing the right medication can be difficult, so it’s worth considering the different options in detail.

Ibuprofen vs Paracetamol for Toothache

Ibuprofen and Paracetamol are similar in that they are painkillers, so they relieve pain symptoms. Paracetamol is considered a milder analgesic, so ibuprofen is more effective for a toothache. However, these two drugs work differently, so sometimes they are taken at the same time.

Ibuprofen vs Tylenol for Tooth Pain

Ibuprofen is more targeted at treating a toothache with swelling, while Tylenol is not. For general pain relief, you can choose Tylenol, which is considered gentler on the stomach. If you plan to combine it with other medications, read the ingredients and avoid those containing acetaminophen.

Ibuprofen vs Aleve for Toothache

Both Ibuprofen and Aleve are used for pain caused by swelling. They differ in their active ingredients and recommended dosages. Ibuprofen is prescribed for acute and unexpected pain. Aleve can be considered an anti-inflammatory drug that lasts longer. It can be taken if fewer doses are needed throughout the day, but to combat long-lasting pain.

Ibuprofen vs Acetaminophen for Tooth Pain

Ibuprofen is recommended for dental problems not only because it relieves pain. It also fights inflammation. Acetaminophen is suitable for mild to moderate pain. It starts working within 30-60 minutes and has the same duration of effect as ibuprofen – 4-6 hours. Regardless of which painkillers you choose, do not abuse them. Use them for temporary pain relief and seek high-quality, consistent treatment.

When Ibuprofen Alone Isn’t Enough

Ibuprofen is a temporary OTC pain reliever, but it is not a substitute for proper treatment. If you suffer from serious diseases, you need a comprehensive approach and a visit to the dentist. 

Ibuprofen does not eliminate the underlying cause, but dulls the pain, so without treatment, it can develop into new symptoms over time. For example, more throbbing pain that radiates to other parts of the body – the ear, head, temples, and neck. A person may develop a fever, experience a drop in productivity, and show signs of infection.

Toothache often worsens at night because you are not distracted by anything else, so you may feel it even more. It is also related to blood stagnation when a person is lying down and the fact that the effect of painkillers may wear off. If ibuprofen does not help, consider these tips:

  • combination of ibuprofen with other drugs (only on the recommendation of a doctor);
  • antibiotics (also on the recommendation of a doctor);
  • folk remedies.

Do not increase the dose of medication on your own. This can lead to side effects and harm to the body.

Safety and Side Effects

When used for a short period of time, the effect of Ibuprofen is quite understandable. It helps restore comfort and eliminate pain. However, any medication has side effects that must be taken into account:

  • headaches and mild dizziness;
  • nausea and vomiting;
  • irritation and pain in the stomach. 

Very rarely, but still possible, are difficulty breathing, chest and abdominal pain, and severe allergic reactions. According to statistics, side effects occur in 1 in 100 people. If you are among these numbers, consult your doctor immediately.

To keep yourself safe, always follow the instructions and don’t mix meds without checking with your doctor first. Stay away from alcohol, as it can make things more toxic. Store your meds the right way – in a calm, dry spot that’s out of reach of kids.

Also, if you use aspirin, do not apply it to your gums. This can cause burns, so only take it internally.

Home Remedies and Natural Methods for Tooth Nerve Pain

What to take for tooth nerve pain? Some people prefer to deal with pain using remedies. These methods can also be used if the pain comes on suddenly but is unbearable. Consider different options to choose the one that works best for you.

Home MethodDescription
RinsingThis is one of the simplest ways to use such decoctions – green tea with grated garlic, salt water with baking soda, or peppermint.
Cold compressesTo do this, prepare cotton swabs. Moisten them beforehand in water with essential oils or strong mint tea. It is recommended to choose essential oils with cloves or calendula, as they have anti-inflammatory and antibacterial properties.
Massage Acupressure may not be suitable for everyone. Apply pressure to specific points – between the thumb and index finger, behind the ankle, and at the base of the index fingernail.

Another important point is getting a good night’s sleep. To reduce discomfort, change your position while sleeping. It is best to sleep on a high pillow with your head elevated. This will reduce the pressure that causes blood to flow and, accordingly, reduce the level of pain.

How Cosmetic Dentistry Can Change Your Life

Are you unsure if cosmetic dentistry is right for you? Not sure if it is worth it? Check out this FREE article that will help you understand!

How Cosmetic Dentistry Can Change Your Life